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How AI concerns are impacting India | What GDP is saying about inflation and rates | How bonds can drive gender equality
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A blood test that can diagnose and monitor the progression of cancer and other diseases?
Liquid biopsy is just one emerging diagnostics innovation that Regnan’s impact investing team believes can enable a transition towards a more proactive and preventative healthcare model.
The procedure has its origins as far back as the 19th century when scientists first detected tumour cells in the bloodstream.
Now liquid biopsy is “the pinnacle of promise in clinical diagnostics,” says Maxine Wille, an analyst in Regnan’s Global Equity Impact Solutions team. Impact investing aims to generate both a financial return and a positive impact on society.
“It’s a non-invasive test. If the promise holds true it will not only help guide treatment decisions for insidious diseases like cancer but also might be used as a screening tool at a very early stage.”
“The promise is that you can now diagnose potentially up to 50 different types of cancers from a single blood draw — that’s why it’s very exciting and why we have decided to take an in-depth look at the sector,” she says.
The value of the liquid biopsy market ranges from $US20 billion to $US100 billion, Maxine says.
Investors should be looking to upweight bonds in their portfolios on a medium-to-long term outlook, argues Pendal’s TIM HEXT in this fast podcast.
Bonds are starting to get towards levels where you could argue in the medium-to-longer term they make a lot more sense.
It’s been very difficult for me as a bond fund manager over the last couple years to recommend that bonds were a good investment down at 1%. The risks were much more to the upside.
Impact investors believe that making a difference makes money. Where does that fit into portfolios in 2022?
“We are finding more and more that investors of all shapes and sizes like the long-term view that impact investors take,” says Tim Crockford, in this fast podcast.
“They like the fact they can understand the themes that will ultimately drive the creation and growth of their capital over the long-term holding periods that impact investors typically take,” says Tim, who heads up Regnan’s equity impact team.
“More and more we see investors resonating with this longer-term view and seeing through the shorter-term noise and volatility that markets typically throw up.
“It means that as an investor I’m going to have to think a little bit more laterally than previously, where I might just compare to benchmarks. But over the longer term, it’s likely to outperform because it is at the beginning of its life cycle.”
Where are the opportunities likely to be found in global equities this year?
Look to the healthcare sector says Pendal Global Select Fund co-manager Chris Lees in this fast podcast.
“I think at the margin, you should be selling some cyclicals because we’ve had the first Covid rebound.
“Now we’re looking at a slowdown. Cyclicals tend to perform not so well and the mid-cycle stocks tend to perform much better as clearly we’re in the mid cycle now.
“That tends to be areas like healthcare.
There are three things to consider when judging whether a green investment is also a good investment.
“Start by make sure what you’re considering is actually green”, says Maxime Le Floch, an analyst with Regnan’s Global Equity Impact Solutions team.
“These are very complex multi-dimensional issues and it’s not just about climate change. It’s also about ocean health, foods, wastewater and many other issues,” he says.
Second, focus on solutions with a strong relative advantage over competitors.
“It’s important to not just look at the environmental benefits of a technology but also how it performs relative to other technologies,” Maxime says.
Finally, focus on long-term opportunities.
“Investors should focus on areas where there are structural growth opportunities – offshore wind, wood-based fibres, water treatment solutions,” he says.
Some 650 million adults are obese (1.9 billion are classed as overweight) and about 4 million die of obesity each year.
But anti-obesity medication is almost non-existent. “It’s a new category,” says Maxime Le Floch, an analyst with Regnan’s impact investment team.
Now investors in Regnan’s Global Equity Impact Solutions fund can say they are helping develop a solution.
Regnan is an investor in Danish diabetes pioneer Novo Nordisk, which is “the poster child for finding a really strong solution that’s miles ahead of competitors in a fast-growing market,” says Maxime.
Novo Nordisk launched its new Wegovy injectable anti-obesity drug in the US last June and expects to launch in Europe later this year.
“Novo Nordisk is investing in clinical trials to prove further the benefits of its treatment, says Maxime.
“It could end up in a new market where there aren’t many solutions and there is a massive opportunity.”
Australia this week sped past the RBA’s 2-to-3% inflation target and caught up with other global economies.
What’s next?
Beyond the headlines of yesterday’s 5.1% CPI result, the contribution of new dwelling purchase price and rents are useful bellwethers, says Anna Hong from Pendal’s Income and Fixed Interest team.
“New dwelling prices came in at 5.7% for this quarter — the highest since the turn of the century. Builders are finding it difficult to quote given the cost pressures they’re facing.”
Meanwhile rents turned the corner, contributing 0.6% this quarter. “Rent growth is accelerating across capital cities and there is more to come.”
This means increased pressure on the RBA to hike rates during the election campaign, says Anna.
“Markets have already priced in aggressive rate hikes in 2022 and a cash rate forecast above 3% by end of 2023. This may come as a shock to mortgage holders.
“The RBA is increasingly looking like it must join other central banks in dampening demand to rein in inflation rather than waiting for supply to fix itself.”
A new Trump Administration, mass restructuring of Japanese corporates, AI adoption and weight loss drugs are some of the trends that will drive global equities in 2025, says Pendal global equities PM Chris Lees.
Chris goes into detail in a new webinar which also features Pendal emerging markets fund manager Ada Chan.
“There are a lot of really exciting mid-cap stocks around the world, in many geographies, in many sectors, where earnings have come through the last few years – but share prices haven’t done much because global markets have been obsessed with the Magnificent Seven [tech stocks],” says Chris.
“Partly the better performance from mid-caps is a result of the Trump election, because the new Administration will be very business friendly.
“We are also seeing a better performance from the financials and cyclicals. I think that is sustainable.”
In the webinar (which is eligible for CPD points), Chris also discusses opportunities in Japan as well as the US and Europe, where second-generation weight loss drugs are in development.
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Get regular insights on investing, market analysis and portfolio management from the experts at Perpetual Group.